Synthesis and characterization of nanostructured copper and lanthanum co?doped zirconia for voltammetric sensing of tumor biomarkers

Nanostructured ZrO2-based materials with their biocompatibility, excellent electrical, and surface charge properties became one of the best candidates for electrochemical sensing applications. Here, synthesis Zr1-xCuxLaxO2 compounds was achieved in nanoscale fully characterized using XRD, TEM, DRS, cyclic voltammetry. A mixture monoclinic cubic phases detected undoped ZrO2 (Z sample, x = 0). For Cu-doped compounds, (ZFW1, 0.05 ZFW2, 0.1), a combination fluorite phase were detected. The intensity higher than that sample. Cu La co-doped samples (ZL1C1, ZL2C2, 0.1) stabilized single structure. Therefore, band gap dropped from (4.8 eV) to (1.49 ZL1C1 sample (2 ZL2C2 Voltammetric neurotransmitter metabolites (vanillylmandelic acid (VMA) homovanillic (HVA)) modified electrodes due acquired high electrocatalytic performance.